The recent increase in federal funding to address the opioid crisis presents health centers the opportunity to expand partnerships with supportive housing and substance use disorder providers. Several states are implementing innovative practices and working with health centers and primary care providers to treat patients with opioid use disorders (OUD). This brief for health center partners summarizes promising practices in three states; explores a managed care organization’s work with its members to address the opioid epidemic; and ways for health centers to incorporate these practices into their OUD services.